THE EFFICACY AND SAFETY OF ICOTINIB IN PATIENTS WITH ADVANCED NON-SMALL CELL LUNG CANCER PREVIOUSLY TREATED WITH CHEMOTHERAPY: A SINGLE-ARM, MULTI-CENTER, PROSPECTIVE STUDY.

Icotinib is a small molecule targeting epidermal growth factor receptor tyrosine kinase, which shows non-inferior efficacy and better safety comparing to gefitinib in previous phase III trial.The present study was designed to further evaluate the efficacy and safety of icotinib in patients with advanced non-small-cell lung cancer (NSCLC) previously

Abstract Tempura is one product of fish processing results.In Indonesia, the development of the tempura fish meatballs.Making tempura include: sorting, washing, peeling vegetables, ingredient mixing, making and frying.Problems tempura product is the save relatively short, therefore it needs the addition of compounds that act as antioxidants and ant

Context: Phenotypic expressions of the congenital cleft hand are variable and might baffle even the experienced as to the choice of surgery.The morphological parameters defining the anomaly dictate not only the functional capacity of the anomalous hand but also the degree of possible surgical restoration.Despite a large number of classifying system

Purpose: To describe a case of leukemic infiltration of Appliance Cords bilateral optic nerves and retina as a site of relapse in a child with T-Cell Acute Lymphoblastic Leukemia (ALL).Observations: We report a 7 year old female who presented one year following initial treatment for T-Cell ALL with visual acuity impairment, bilateral optic nerve in

Abstract Matrix Metalloproteases (MMPs) are an important family of proteases that play crucial roles in key cellular and disease processes.Therefore, MMPs constitute important targets for drug design, development and delivery.Advanced proteomic technologies have identified type-specific target substrates; however, the complete repertoire of MMP sub